Home > Books > Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers
Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers
View PDF

Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers

Publication Year: 2010
Edition: 1st
Authors/Editor: Jabbari, Esmaiel.; Khademhosseini, Ali
Publisher: World Scientific Publishing Co, Inc.
ISBN: 978-9-814-29567-3
  • Description
  • Details
  • Collections

There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials.

Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field.

This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials.

  • Platform:
    Ovid
  • Publisher: World Scientific Publishing Co, Inc.
  • Product Type: Book
  • Author/Editor: Jabbari, Esmaiel.; Khademhosseini, Ali
  • ISBN: 978-9-814-29567-3
  • Specialty:
    Biomedical Engineering
  • Language: English
  • Edition: 1st
  • Pages: 432
  • Illustrations: 0
  • Year: 2010

Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers is included in the following Collections:

Free Instant Access
This Month

JOTM
Social Policy & Practice A comprehensive bibliographic database, SSP helps professionals, practitioners, researchers, and students to understand, plan, and evaluate existing and future social policy.
JOTM
Visible Body Muscle Premium 3D interactive specialty module illustrates the basic movement of a variety of muscles throughout the human body as they interact with bone, nerves, and ligaments.
JOTM
Anesthesia & Analgesia Official journal of the International Anesthesia Research Society, provides the practice-oriented, clinical research to keep current and provide optimal care to patients.
JOTM
PAIN® Official publication of the International Association for the Study of Pain, publishes original research on the nature, mechanisms and treatment of pain.

Noteworthy

Doody's Featured Books
Harborview Illustrated Tips and Tricks in Fracture Surgery, 2nd Alumni Edition
Graduates of the Orthopaedic Trauma program at the University of Washington Harborview Medical Center provide tips and tricks gleaned from their years of professional practice.

Illustrated Tips and Tricks in Sports Medicine Surgery
Succinct, precise information from a wide range of experts and prestigious institutions on tackling technical problems in sports medicine surgery.