Home > Books > Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers
Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers
View PDF

Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers

Publication Year: 2010
Edition: 1st
Authors/Editor: Jabbari, Esmaiel.; Khademhosseini, Ali
Publisher: World Scientific Publishing Co, Inc.
ISBN: 978-9-814-29567-3
  • Description
  • Details
  • Collections

There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials.

Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field.

This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials.

  • Platform:
    Ovid
  • Publisher: World Scientific Publishing Co, Inc.
  • Product Type: Book
  • Author/Editor: Jabbari, Esmaiel.; Khademhosseini, Ali
  • ISBN: 978-9-814-29567-3
  • Specialty:
    Biomedical Engineering
  • Language: English
  • Edition: 1st
  • Pages: 432
  • Illustrations: 0
  • Year: 2010

Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers is included in the following Collections:

Free Instant Access
This Month

JOTM
Embase® The Embase database is the most trusted source of global, evidence-based pharmacological and biomedical research with over 30 million bibliographic records dating back to 1947.
JOTM
Visible Body Heart & Circulatory Premium This interactive 3D Atlas is a deep dive into the heart and circulatory system for learning, reference, and patient education.
JOTM
Circulation Research Presents peer-reviewed reports on research advances in biology, biochemistry, biophysics, cellular and molecular biology, morphology, pathology, physiology, and pharmacology.
JOTM
Regional Anesthesia & Pain Medicine Publishes peer-reviewed scientific and clinical studies to advance the understanding and application of regional techniques for surgical anesthesia and postoperative analgesia.

Noteworthy

Doody's Featured Books
Manual of Valvular Heart Disease
Portable and clinically oriented, this full-color handbook is a unique and timely guide to valvular heart disease and percutaneous coronary interventions.

Khonsari's Cardiac Surgery: Safeguards and Pitfalls in Operative Technique
Details the most important techniques in a concise, readable, and richly illustrated format, with a focus on avoiding and managing surgical pitfalls and complications.