Home > Books > Metallothioneins in Biochemistry and Pathology
Metallothioneins in Biochemistry and Pathology
View PDF

Metallothioneins in Biochemistry and Pathology

Publication Year: 2008
Edition: 1st
Authors/Editor: Zatta, Paolo
Publisher: World Scientific Publishing Co, Inc.
ISBN: 978-9-812-77893-2
  • Description
  • Details
  • Collections

This important book explores the role of metallothioneins (MT's) in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.

Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.

  • Platform:
    Ovid
  • Publisher: World Scientific Publishing Co, Inc.
  • Product Type: Book
  • Author/Editor: Zatta, Paolo
  • ISBN: 978-9-812-77893-2
  • Specialty:
    Biochemistry & Biophysics
    Pathology
  • Language: English
  • Edition: 1st
  • Pages: 336
  • Illustrations: 0
  • Year: 2008

Metallothioneins in Biochemistry and Pathology is included in the following Collections:

Free Instant Access
This Month

JOTM
Social Policy & Practice A comprehensive bibliographic database, SSP helps professionals, practitioners, researchers, and students to understand, plan, and evaluate existing and future social policy.
JOTM
Visible Body Muscle Premium 3D interactive specialty module illustrates the basic movement of a variety of muscles throughout the human body as they interact with bone, nerves, and ligaments.
JOTM
Anesthesia & Analgesia Official journal of the International Anesthesia Research Society, provides the practice-oriented, clinical research to keep current and provide optimal care to patients.
JOTM
PAIN® Official publication of the International Association for the Study of Pain, publishes original research on the nature, mechanisms and treatment of pain.

Noteworthy

Doody's Featured Books
Harborview Illustrated Tips and Tricks in Fracture Surgery, 2nd Alumni Edition
Graduates of the Orthopaedic Trauma program at the University of Washington Harborview Medical Center provide tips and tricks gleaned from their years of professional practice.

Illustrated Tips and Tricks in Sports Medicine Surgery
Succinct, precise information from a wide range of experts and prestigious institutions on tackling technical problems in sports medicine surgery.