Home > Books > Oncology Clinical Trials: Successful Design, Conduct and Analysis
Oncology Clinical Trials: Successful Design, Conduct and Analysis
View PDF

Oncology Clinical Trials: Successful Design, Conduct and Analysis

Publication Year: 2018
Edition: 2nd Ed.
Authors/Editor: Kelly, William Kevin; Halabi, Susan
Publisher: Springer Publishing Company
ISBN: 978-0-826-16872-6
  • Description
  • Details

The second edition of Oncology Clinical Trials has been thoroughly revised and updated and now contains the latest designs and methods of conducting and analyzing cancer clinical trials in the era of precision medicine with biologic agents—including trials investigating the safety and efficacy of targeted therapies, immunotherapies, and combination therapies as well as novel radiation therapy modalities.

Now divided into six sections this revamped book provides the necessary background and expert guidance from the principles governing oncology clinical trials to the innovative statistical design methods permeating the field; from conducting trials in a safe and effective manner, analyzing and interpreting the data, to a forward-looking assessment and discussion of regulatory issues impacting domestic, international, and global clinical trials.

Considered by many as the gold standard reference on oncology clinical trials in the field, the second edition continues to provide examples of real-life flaws and real-world examples for how to successfully design, conduct and analyze quality clinical trials and interpret them. With chapters written by oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives, this volume provides a comprehensive guide in the design, conduct, monitoring, analysis, and reporting of clinical trials in oncology.

New to this Edition:
- Outlines how to design clinical trials with and without biomarker testing—including genomics-based “basket” trials, and adaptive trials for all phases during treatment and quality-of-life trials
- Includes new chapters on immunotherapy trials, radiation therapy trials, multi-arm trials, meta-analysis and adaptive design, use of genomics, dose modifications and use of ancillary treatments in investigational studies, establishing surrogate endpoints, practical issues with correlative studies, cost-effectiveness analysis, and more
- Comprehensively covers all regulatory aspects in the pursuit of global oncology trials

  • Platform:
    Ovid
  • Publisher: Springer Publishing Company
  • Product Type: Book
  • Author/Editor: Kelly, William Kevin; Halabi, Susan
  • ISBN: 978-0-826-16872-6
  • Specialty:
    Epidemiology
    Hematology
    Oncology
  • Language: English
  • Edition: 2nd Ed.
  • Pages: 600
  • Illustrations: 0
  • Year: 2018

Free Instant Access
This Month

JOTM
GIDEON: Global Infectious Diseases & Epidemiology Online Network Features up-to-date information and visual tools for diagnosing diseases and following the latest trends in epidemiology and treatment.
JOTM
Derwent Drug File Derwent Drug File is the definitive source for information on all aspects of drug development, synthesis, evaluation, manufacture and use.
JOTM
Obstetrics & Gynecology Official journal of the American College of Obstetricians and Gynecologists (ACOG), promotes excellence in the clinical practice of obstetrics and gynecology and closely related fields.
JOTM
American Journal of Health-System Pharmacy Publishes peer reviewed scientific papers on contemporary drug therapy and pharmacy practice innovations in hospitals and health systems.

Noteworthy

Doody's Featured Books
Cancer Immunotherapy Principles and Practice
The authoritative reference on cancer immunobiology and the immunotherapy treatments that harness the immune system to combat malignant disease.

Pediatric Neuroradiology: Clinical Practice Essentials
Offers concise guidelines on very complex topics related to the areas of pediatric neuroradiology in which it is crucial that radiologists make correct diagnoses.