Home > Books > Preclinical Development Handbook: Toxicology
Preclinical Development Handbook: Toxicology
View PDF

Preclinical Development Handbook: Toxicology

Publication Year: 2008
Edition: 1st
Authors/Editor: Gad, Shayne Cox
Publisher: Wiley
ISBN: 978-0-470-24846-1
  • Description
  • Details

A clear, straightforward resource to guide you through preclinical drug development.

Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current methods and techniques.

Each chapter was written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.

Among the key topics covered are:
* In vitro mammalian cytogenetics tests
* Phototoxicity
* Carcinogenicity studies
* The pharmacogenomics of personalized medicine
* Bridging studies
* Toxicogenomics and toxicoproteomics

Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage.

This is a hands-on guide for pharmaceutical scientists involved in preclinical testing,enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.

  • Platform:
    Ovid
  • Publisher: Wiley
  • Product Type: Book
  • Author/Editor: Gad, Shayne Cox
  • ISBN: 978-0-470-24846-1
  • Specialty:
    Pharmacology
  • Language: English
  • Edition: 1st
  • Pages: 1080
  • Illustrations: 0
  • Year: 2008

Free Instant Access
This Month

JOTM
Visible Body Anatomy & Physiology Interactive 3D teaching resource, comprised of 50 modules that incorporate 3D models, illustrations, and animations to present core content of basic anatomy and physiology courses.
JOTM
Global Health The only specialist bibliographic abstracting and indexing database dedicated to public health. Global Health contains over 3 million scientific records from 1973 to the present, derived from over 7,300 journals, reports, books and conferences.
JOTM
Neurology® This official journal of the American Academy of Neurology features best practices, evidence-based research and articles on topics that directly affect practicing neurologists.
JOTM
The American Journal of Surgical Pathology Official Journal of The Arthur Purdy Stout Society of Surgical Pathologists and The Gastrointestinal Pathology Society. Contains original articles, review articles, detailed case reports, and special features, enhanced by superb illustrations.

Noteworthy

Doody's Featured Books
21st Century Nursing Leadership
Exciting and indispensable tool that will steer current and emerging nurse leaders through the issues of nursing practice that matter most.

Bethesda Handbook of Clinical Hematology
Provides concise, up-to-date coverage of need to know information on the diagnosis and treatment of blood and bone marrow disorders.