Home > Books > Preclinical Development Handbook: Toxicology
Preclinical Development Handbook: Toxicology
View PDF

Preclinical Development Handbook: Toxicology

Publication Year: 2008
Edition: 1st
Authors/Editor: Gad, Shayne Cox
Publisher: Wiley
ISBN: 978-0-470-24846-1
  • Description
  • Details

A clear, straightforward resource to guide you through preclinical drug development.

Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current methods and techniques.

Each chapter was written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.

Among the key topics covered are:
* In vitro mammalian cytogenetics tests
* Phototoxicity
* Carcinogenicity studies
* The pharmacogenomics of personalized medicine
* Bridging studies
* Toxicogenomics and toxicoproteomics

Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage.

This is a hands-on guide for pharmaceutical scientists involved in preclinical testing,enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.

  • Platform:
    Ovid
  • Publisher: Wiley
  • Product Type: Book
  • Author/Editor: Gad, Shayne Cox
  • ISBN: 978-0-470-24846-1
  • Specialty:
    Pharmacology
  • Language: English
  • Edition: 1st
  • Pages: 1080
  • Illustrations: 0
  • Year: 2008

Free Instant Access
This Month

JOTM
GIDEON: Global Infectious Diseases & Epidemiology Online Network Features up-to-date information and visual tools for diagnosing diseases and following the latest trends in epidemiology and treatment.
JOTM
Derwent Drug File Derwent Drug File is the definitive source for information on all aspects of drug development, synthesis, evaluation, manufacture and use.
JOTM
Obstetrics & Gynecology Official journal of the American College of Obstetricians and Gynecologists (ACOG), promotes excellence in the clinical practice of obstetrics and gynecology and closely related fields.
JOTM
American Journal of Health-System Pharmacy Publishes peer reviewed scientific papers on contemporary drug therapy and pharmacy practice innovations in hospitals and health systems.

Noteworthy

Doody's Featured Books
Cancer Immunotherapy Principles and Practice
The authoritative reference on cancer immunobiology and the immunotherapy treatments that harness the immune system to combat malignant disease.

Pediatric Neuroradiology: Clinical Practice Essentials
Offers concise guidelines on very complex topics related to the areas of pediatric neuroradiology in which it is crucial that radiologists make correct diagnoses.