Home > Books > Clinical Trials in Psychopharmacology: A Better Brain
Clinical Trials in Psychopharmacology: A Better Brain
View PDF

Clinical Trials in Psychopharmacology: A Better Brain

Publication Year: 2010
Edition: 2nd
Authors/Editor: Hertzman, Marc and Adler, Lawrence
Publisher: Wiley
ISBN: 978-0-470-74076-7
  • Description
  • Details

The authors take a critical look at recent developments and present a series of trenchant and challenging observations

Although clinical trials were virtually unheard of in psychiatry for many years, they are now the gold standard for judging whether drugs are safe and useful. But should they be? What is the true status of clinical trials? Even when they ostensibly demonstrate a benefit of a certain treatment, the strict patient selection criteria, poor compliance and high drop-out rate leave the conclusions open to question. Are the new treatments really better or more cost-effective than the old? Do they have fewer side effects?

Clearly written, this book provides immediate access to new developments across the spectrum of drug testing. It's provocative reading for psychiatrists, pharmacologists and all those interested in improved drug treatments for patients with mental illness.

Section I examines the significant changes in law and the regulatory environment that have occurred during the past ten years. Has fossilization handicapped the US Food and Drug Administration in promoting treatment advances? How can the plethora of findings be regulated? This is particularly pertinent in genomic studies and there are two chapters addressing the impact of genomics on psychiatric research. This section also addresses the role of women in drug trials – a group long excluded but now demanding a part, for without testing how can optimal treatments be devised?

The next two Sections highlight clinical trials in the major areas of psychiatric pharmacological treatment, including Mood Disorders, especially Bipolar, Anxiety Disorders, and addictions. Chapters on pharmacological treatments for Eating Disorders, Attention Deficit Disorder, Autism and Asperger’s Syndrome, and Impulse Control Disorder represent the latest thinking on these subjects.

The final Section contains a consummate example of out-of-the [Western]- box thinking, namely consideration of herbal medicines – used by a large number of patients, with or without medical supervision. We conclude with a close look at the problem of side effects, then selected thoughts about methodology.

Clearly written, the text provides immediate access to new developments across the spectrum of drug testing. Clinical Trials in Psychopharmacology: A Better Brain is provocative reading for psychiatrists, pharmacologists and all those interested in improved drug treatments for patients with mental illness.

  • Platform:
    Ovid
  • Publisher: Wiley
  • Product Type: Book
  • Author/Editor: Hertzman, Marc and Adler, Lawrence
  • ISBN: 978-0-470-74076-7
  • Specialty:
    Psychopharmacology
  • Language: English
  • Edition: 2nd
  • Pages: 406
  • Illustrations: 0
  • Year: 2010

Free Instant Access
This Month

JOTM
Biomedical Research Grants—UberResearch NEW! UberResearch is a searchable database of awarded research funding that includes more than 600,000 indexed records. And now it's available on the Ovid® platform!
JOTM
The Philosopher's Index The Philosopher's Index is a bibliographic database with informative author-written abstracts covering scholarly research in the fifteen fields of philosophy, published in journals and books since 1940.
JOTM
Evidence-Based Practice Evidence-Based Practice is a quarterly journal focused on topics relevant to the daily practice of family medicine and includes content addressing timely and pertinent questions related to patient care.
JOTM
Stroke An official journal of the American Heart Association, Stroke publishes reports of clinical and basic investigation of any aspect of the cerebral circulation and its diseases from many disciplines.

Noteworthy

Doody's Featured Books
Shields' General Thoracic Surgery, 8th Edition
Your #1 resource for comprehensive coverage of both open and endoscopic surgical techniques, with commentary from more than 150 global experts in the field.

The Washington Manual of Echocardiography, 2nd Edition
Essential information you need to successfully perform and read echocardiograms, as well as to identify valvular heart disease, cardiac myopathies, and congenital anomalies.